Stages and Symptoms

As symptoms worsen over time, the disease will progress through 3 stages.

In the early stage, you may notice some mild memory loss, but as the disease progresses to the moderate and severe stages, you may notice that new symptoms appear or existing ones worsen.

  • The moderate stage is often the longest stage, where your loved one will require a greater level of care and will typically experience the fastest rate of decline. Their symptoms will progress, and you may notice new symptoms.
  • When they've progressed to the severe stage, they may not be able to communicate and may lack control of their bowel or bladder.

Recognize the stages and symptoms of Alzheimer's disease

What should I do if I notice changes in my loved one's symptoms?

Older man with younger man image

Examples of moderate stage Alzheimer’s symptoms

  • Difficulty managing personal finances like paying bills
  • Difficulty with household tasks like laundry and making meals
  • Problems with personal care like bathing, grooming, and toileting
  • Wandering or getting lost
  • Changes in sleep patterns
  • Feeling moody, withdrawn, or detached
  • Forgetfulness about one's own personal history
  • Unable to recall their own address or phone number
  • Needing help choosing proper clothing for the season
  • Continuously repeating stories

Examples of severe stage Alzheimer’s symptoms

  • May not recognize oneself or family
  • May not communicate
  • Lack of control of bowel or bladder
  • Groaning, moaning, or grunting
  • Needing help with all activities of daily living

NAMZARIC is a prescription medicine approved to treat moderate to severe Alzheimer’s disease in patients who are taking donepezil hydrochloride 10 mg.

There is no evidence that NAMZARIC prevents or slows the underlying disease process in patients with Alzheimer's disease.

Important Risk Information

NAMZARIC should not be taken by anyone who: has an allergy to memantine HCl, donepezil HCl, medicines that contain piperidines, or any of the ingredients in NAMZARIC.

Before taking NAMZARIC, tell the doctor about all of the patient’s medical conditions, including:

  • heart problems including an irregular, slow, or fast heartbeat
  • asthma or lung problems
  • seizures
  • stomach ulcers
  • bladder, kidney, or liver problems
  • any surgical, dental, or other medical procedures scheduled when anesthesia may be used

Tell the doctor about all the medicines the patient takes, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of NAMZARIC?

NAMZARIC may cause serious side effects, including:

  • muscle problems in patients given anesthesia
  • slow heartbeat and fainting. This happens
    more often in people with heart
    problems. Call the doctor right away if
    the patient faints while taking
    NAMZARIC.
  • more stomach acid. This raises the
    chance of ulcers and bleeding especially
    when taking NAMZARIC. The risk is
    higher for patients who have had ulcers,
    or
    take aspirin or other NSAIDs.
  • nausea and vomiting
  • difficulty passing urine
  • seizures
  • worsening of lung problems in people
    with asthma or other lung disease

The most common side effects of memantine HCl include: headache, diarrhea, and dizziness.

The most common side effects of donepezil HCl include: diarrhea, not wanting to eat (anorexia), and bruising.

These are not all the possible side effects of NAMZARIC.

Please also see full Prescribing Information, including Patient Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.

Expand

USE

NAMZARIC is a prescription medicine approved to treat moderate to severe Alzheimer’s disease in patients who are taking donepezil hydrochloride 10 mg.

There is no evidence that NAMZARIC prevents or slows the underlying disease process in patients with Alzheimer's disease.

Important Risk Information

NAMZARIC should not be taken by anyone who: has an allergy to memantine HCl, donepezil HCl, medicines that contain piperidines, or any of the ingredients in NAMZARIC.

Before taking NAMZARIC, tell the doctor about all of the patient’s medical conditions, including:

  • heart problems including an irregular, slow, or fast heartbeat
  • asthma or lung problems
  • seizures
  • stomach ulcers
  • bladder, kidney, or liver problems
  • any surgical, dental, or other medical procedures scheduled when anesthesia may be used

Tell the doctor about all the medicines the patient takes, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of NAMZARIC?

NAMZARIC may cause serious side effects, including:

  • muscle problems in patients given anesthesia
  • slow heartbeat and fainting. This happens
    more often in people with heart
    problems. Call the doctor right away if
    the patient faints while taking
    NAMZARIC.
  • more stomach acid. This raises the
    chance of ulcers and bleeding especially
    when taking NAMZARIC. The risk is
    higher for patients who have had ulcers,
    or
    take aspirin or other NSAIDs.
  • nausea and vomiting
  • difficulty passing urine
  • seizures
  • worsening of lung problems in people
    with asthma or other lung disease

The most common side effects of memantine HCl include: headache, diarrhea, and dizziness.

The most common side effects of donepezil HCl include: diarrhea, not wanting to eat (anorexia), and bruising.

These are not all the possible side effects of NAMZARIC.

Indication

NAMZARIC is a prescription medicine approved to treat moderate to severe Alzheimer’s disease in patients who are taking donepezil hydrochloride 10 mg.

There is no evidence that NAMZARIC prevents or slows the underlying disease process in patients with Alzheimer's disease.

Please also see full Prescribing Information, including Patient Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.