Recognize the stages and symptoms of Alzheimer's disease

Having a better understanding of how Alzheimer's progresses can help you care for your loved one

As symptoms worsen over time, the disease will progress through 3 stages. In the early stage, you may notice some mild memory loss, but, as the disease progresses to the moderate and severe stages, you may notice new symptoms appear or existing ones worsen.

  • The moderate stage is often the longest stage, where your loved one will require a greater level of care and will typically experience the fastest rate of decline. Their symptoms will progress and you may notice new symptoms

According to a U.S.-based survey, nearly 50% of patients with Alzheimer's disease are already in the moderate to severe stages when diagnosed.

  • When they’ve progressed to the severe stage, they may lose the ability to perform daily activities, like carrying on a conversation or even being aware of their surroundings, and may be entirely dependent on your help

What should I do if I notice changes in my loved one's symptoms?

Noticing a change in your loved one's symptoms may mean their Alzheimer’s has progressed. It’s important to make an appointment with the doctor as soon as possible. That way, the doctor can make an informed decision about whether it’s time to adjust your loved one’s treatment for moderate Alzheimer’s disease.

Some examples of moderate stage Alzheimer’s symptoms
  • Difficulty managing personal finances (paying bills)
  • Difficulty with household tasks (laundry, making meals)
  • Problems with personal care (bathing, grooming, toileting)
  • Wandering or getting lost
  • Changes in sleep patterns
  • Feeling moody, withdrawn, or detached
  • Forgetfulness about one's own personal history
  • Being unable to recall their own address or phone number
  • Needing help choosing proper clothing for the season
  • Continuously repeating stories
Examples of severe stage Alzheimer’s symptoms
  • May not recognize oneself or family
  • May not communicate
  • Lack of control of bowel or bladder
  • Groaning, moaning, or grunting
  • Needing help with all activities of daily living

The lists above include examples of common symptoms in the moderate and severe stages of Alzheimer’s disease.

If you’ve noticed a change in your loved one’s Alzheimer's symptoms, make an appointment with their doctor as soon as possible.

NAMZARIC is a prescription medicine approved to treat moderate to severe Alzheimer’s disease in patients who are taking donepezil hydrochloride 10 mg, the active ingredient in Aricept®.

Important Risk Information

NAMZARIC should not be taken by anyone who: has an allergy to memantine HCl, donepezil HCl, medicines that contain piperidines, or any of the ingredients in NAMZARIC.

Before taking NAMZARIC, tell the doctor about all of the patient’s medical conditions, including:

  • heart problems including an irregular, slow, or fast heartbeat
  • asthma or lung problems
  • seizures
  • stomach ulcers
  • bladder, kidney, or liver problems
  • any surgical, dental, or other medical procedures scheduled when anesthesia may be used

Tell the doctor about all the medicines the patient takes, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of NAMZARIC?

NAMZARIC may cause serious side effects, including:

  • muscle problems in patients given anesthesia
  • slow heartbeat and fainting. This happens more often in people with heart problems. Call the doctor right away if the patient faints while taking NAMZARIC.
  • more stomach acid. This raises the chance of ulcers and bleeding especially when taking NAMZARIC. The risk is higher for patients who have had ulcers, or take aspirin or other NSAIDs.
  • nausea and vomiting
  • difficulty passing urine
  • seizures
  • worsening of lung problems in people with asthma or other lung disease

The most common side effects of memantine HCl include: headache, diarrhea, and dizziness.

The most common side effects of donepezil HCl include: diarrhea, not wanting to eat (anorexia), and bruising.

These are not all the possible side effects of NAMZARIC.

Please see full Prescribing Information, including Patient Information.

Aricept® is a trademark used by Eisai Inc. under license from Eisai R&D Management Co., Ltd.

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NAMZARIC is a prescription medicine approved to treat moderate to severe Alzheimer’s disease in patients who are taking donepezil hydrochloride 10 mg, the active ingredient in Aricept®.

Important Risk Information

NAMZARIC should not be taken by anyone who: has an allergy to memantine HCl, donepezil HCl, medicines that contain piperidines, or any of the ingredients in NAMZARIC.

Before taking NAMZARIC, tell the doctor about all of the patient’s medical conditions, including:

  • heart problems including an irregular, slow, or fast heartbeat
  • asthma or lung problems
  • seizures
  • stomach ulcers
  • bladder, kidney, or liver problems
  • any surgical, dental, or other medical procedures scheduled when anesthesia may be used

Tell the doctor about all the medicines the patient takes, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of NAMZARIC?

NAMZARIC may cause serious side effects, including:

  • muscle problems in patients given anesthesia
  • slow heartbeat and fainting. This happens more often in people with heart problems. Call the doctor right away if the patient faints while taking NAMZARIC.
  • more stomach acid. This raises the chance of ulcers and bleeding especially when taking NAMZARIC. The risk is higher for patients who have had ulcers, or take aspirin or other NSAIDs.
  • nausea and vomiting
  • difficulty passing urine
  • seizures
  • worsening of lung problems in people with asthma or other lung disease

The most common side effects of memantine HCl include: headache, diarrhea, and dizziness.

The most common side effects of donepezil HCl include: diarrhea, not wanting to eat (anorexia), and bruising.

These are not all the possible side effects of NAMZARIC.

Please see full Prescribing Information, including Patient Information.

Aricept® is a trademark used by Eisai Inc. under license from Eisai R&D Management Co., Ltd.