The convenience of once-a-day dosing

If your loved one with moderate to severe Alzheimer's disease is taking donepezil HCl 10 mg and not currently on memantine HCl,* ask their doctor if NAMZARIC® is right for them

NAMZARIC can provide combination therapy without having to add more pills

NAMENDA® (memantine HCl) twice daily or NAMENDA XR® (memantine HCl).

The dose will gradually increase from 7 mg/10 mg to the maximum dose of 28 mg/10 mg over 4 weeks.

If the doctor thinks NAMZARIC is right for your loved one, they may give them a Starter Pack to help transition to NAMZARIC

Your loved one can get started on NAMZARIC by following this schedule:

Taken once daily in the evening. The dose of NAMZARIC will gradually increase over 4 weeks

Your loved one should stay on the same dose for at least 7 days

The dose should only be increased if the previous dose was well tolerated

Color-coded capsules help your loved one reach the recommended target dose (28 mg/10 mg once daily)

  • For patients with severe renal impairment, NAMZARIC 14 mg/10 mg once daily is the highest recommended dose

Is your loved one currently taking donepezil and memantine?

If your loved one is taking donepezil HCl 10 mg and NAMENDA® (memantine HCl) twice daily or once-a-day NAMENDA XR® (memantine HCl), ask their doctor if NAMZARIC is right for them

Currently taking NAMENDA and donepezil?

The doctor may instruct you to transition your loved one directly to once-a-day NAMZARIC the day after their last dose of NAMENDA and donepezil.

Currently taking NAMENDA XR and donepezil?

The doctor may instruct you to transition your loved one directly to once-a-day NAMZARIC the day after their last dose of NAMENDA XR and donepezil.

How should NAMZARIC be taken?

  • NAMZARIC should be taken with or without food in the evening, just before bedtime, as prescribed by your loved one's doctor
  • If your loved one misses one dose of NAMZARIC, take only the next dose as scheduled. Do not take 2 doses of NAMZARIC at the same time
  • The capsules should be swallowed whole or opened and sprinkled on applesauce. They should not be divided, crushed, or chewed

NAMZARIC is a prescription medicine approved to treat moderate to severe Alzheimer’s disease in patients who are taking donepezil hydrochloride 10 mg, the active ingredient in Aricept®.

There is no evidence that NAMZARIC prevents or slows the underlying disease process in patients with Alzheimer's disease.

Important Risk Information

NAMZARIC should not be taken by anyone who: has an allergy to memantine HCl, donepezil HCl, medicines that contain piperidines, or any of the ingredients in NAMZARIC.

Before taking NAMZARIC, tell the doctor about all of the patient’s medical conditions, including:

  • heart problems including an irregular, slow, or fast heartbeat
  • asthma or lung problems
  • seizures
  • stomach ulcers
  • bladder, kidney, or liver problems
  • any surgical, dental, or other medical procedures scheduled when anesthesia may be used

Tell the doctor about all the medicines the patient takes, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of NAMZARIC?

NAMZARIC may cause serious side effects, including:

  • muscle problems in patients given anesthesia
  • slow heartbeat and fainting. This happens more often in people with heart problems. Call the doctor right away if the patient faints while taking NAMZARIC.
  • more stomach acid. This raises the chance of ulcers and bleeding especially when taking NAMZARIC. The risk is higher for patients who have had ulcers, or take aspirin or other NSAIDs.
  • nausea and vomiting
  • difficulty passing urine
  • seizures
  • worsening of lung problems in people with asthma or other lung disease

The most common side effects of memantine HCl include: headache, diarrhea, and dizziness.

The most common side effects of donepezil HCl include: diarrhea, not wanting to eat (anorexia), and bruising.

These are not all the possible side effects of NAMZARIC.

Please see full Prescribing Information, including Patient Information.

Aricept® is a trademark used by Eisai Inc. under license from Eisai R&D Management Co., Ltd.

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NAMZARIC is a prescription medicine approved to treat moderate to severe Alzheimer’s disease in patients who are taking donepezil hydrochloride 10 mg, the active ingredient in Aricept®.

There is no evidence that NAMZARIC prevents or slows the underlying disease process in patients with Alzheimer's disease.

Important Risk Information

NAMZARIC should not be taken by anyone who: has an allergy to memantine HCl, donepezil HCl, medicines that contain piperidines, or any of the ingredients in NAMZARIC.

Before taking NAMZARIC, tell the doctor about all of the patient’s medical conditions, including:

  • heart problems including an irregular, slow, or fast heartbeat
  • asthma or lung problems
  • seizures
  • stomach ulcers
  • bladder, kidney, or liver problems
  • any surgical, dental, or other medical procedures scheduled when anesthesia may be used

Tell the doctor about all the medicines the patient takes, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of NAMZARIC?

NAMZARIC may cause serious side effects, including:

  • muscle problems in patients given anesthesia
  • slow heartbeat and fainting. This happens more often in people with heart problems. Call the doctor right away if the patient faints while taking NAMZARIC.
  • more stomach acid. This raises the chance of ulcers and bleeding especially when taking NAMZARIC. The risk is higher for patients who have had ulcers, or take aspirin or other NSAIDs.
  • nausea and vomiting
  • difficulty passing urine
  • seizures
  • worsening of lung problems in people with asthma or other lung disease

The most common side effects of memantine HCl include: headache, diarrhea, and dizziness.

The most common side effects of donepezil HCl include: diarrhea, not wanting to eat (anorexia), and bruising.

These are not all the possible side effects of NAMZARIC.

Indication

NAMZARIC is a prescription medicine approved to treat moderate to severe Alzheimer’s disease in patients who are taking donepezil hydrochloride 10 mg, the active ingredient in Aricept®.

Please see full Prescribing Information, including Patient Information.

Aricept® is a trademark used by Eisai Inc. under license from Eisai R&D Management Co., Ltd.